Research & Development
Our proprietory platform technology forms the basis for our innovative product development. This technology enables us to evaluate novel compositions from food chain raw materials, allowing us to create intellectual property for long term value creation.
212
Patents
granted
granted
with
92
Patents
applied
applied
and
34
Patents
total
total
We collaborate with reputed academic institutions and research organizations to ensure robust innovative products.
72
papers in
peer reviewed journals
peer reviewed journals
with
59
conference presentations
Our research & development excel in
Our research & development excel in
fenugreek seeds
cinnamon bark
gotu kola leaves
Fenugreek (Scientific Name: Trigonella foenum-gracum) seeds have stood the test of time as a medicinal plant. Fenugreek is an integral part of many traditional healing systems. The multiple medicinal benefits of Fenugreek seeds have led to a focus on it as a nutritional supplement.
We, at Indus Biotech, have pioneered research on Fenugreek seeds. Our R&D has led to the discovery of many bioactive molecules in Fenugreek seeds. Our science has harnessed the potential of these molecules for promising healthcare applications.
Cinnamon (Scientific Name: Cinnamomum zeylanicum) bark is a traditional treatment for inflammation, pain, fever and arthritis. Cinnamon bark also boosts immunity.
Our research on Cinnamon bark has led to the identification of specific polyphenols effective against chronic immune and infectious conditions including allergic rhinitis.
Gotu Kola (Scientific Name: Centella asiatica) leaves are part of Asian and African healing systems. The medicinal properties of Gotu Kola are derived from constituents called Triterpenes.
With our platform technology we have identified and characterized our patented composition of Triterpene molecules.
We have developed patented standardized products from fenugreek seeds containing:
Hydroxyisolueicne
(a major amino acid)
(a major amino acid)
Trigonelline
(a major alkaloid)
(a major alkaloid)
Oligosaccharide/
Galactomannan/
Soluble Fibers
Galactomannan/
Soluble Fibers
Glycosides and
Furostenol Saponins
Furostenol Saponins
Type A Proanthocyanidin Polyphenol
Asiaticoside
Madecassoside
List of Patents and Publications
List of Patents and Publications
Raw Material
Products
Sr. No.
Year
Title
Conferences
1
Preclinical efficacy of intranasal administration of standardised extract of Centella asiatica leaves (INDCA) on Nitroglycerine (NTG) Induced Chronic Migraine Pain in laboratory animals
2019
Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, India AICTE, Govt. of India and Society for Ethnopharmacology India-Pune Chapter:
2
Preclinical Efficacy of Intranasal Administration of Standardised Extract of Centella asiatica leaves (INDCA) on Nitroglycerine (NTG) Induced Chronic Migraine Pain in Laboratory Animals [OEP11]
2019
Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune Society of Ethnopharmacology, Pune Chapter: p.10.
3
Preclinical efficacy of intranasal INDCA on chronic unpredictable mild stress (CUMS) induced depression and cognitive deficit in laboratory rats [ Received G. Achari Prize Award]
2019
Hyderabad,, India National Institute of Nutrition, Hyderabad, Telangana State, India:
4
Safety Pharmacology of Intranasal Administration of Standardized Extract of Centella asiatica Leaves (INDCA) on Central Nervous System and Cardiovascular System using ICH Guidelines in Wistar Rats [PEP50]
2019
Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune Society of Ethnopharmacology, Pune Chapter: p.76.
5
Safety Pharmacology of Intranasal Administration of Standardized Extract of Centella asiatica Leaves (INDCA) on Central Nervous System and Cardiovascular System using ICH Guidelines in Wistar Rats
2019
Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune Society of Ethnopharmacology, Pune Chapter: p.47.
6
Fenugreek polyphenol glycosides: Wellness and medicinal uses
2017
University of Vienna, Austria:
7
Prenatal developmental toxicity study of glycoside based Standardized extract from Trigonella foenum-graecum in rats [P4]
2016
Phytocongress 2016, Center for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, Tanjavur, India: p.38.
8
Novel Isolation and characterization of Trigonelline monohydrate
2016
Phytocongress 2016, Center for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, Tanjavur, India: p.21.
9
Prenatal developmental toxicity study of glycoside based Standardized extract from Trigonella foenum?graecum in rats [P4]
2016
Center for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, Tanjavur, India: p.38.
10
Natural Products Discovery and Development: Opportunities and Challenges (O1]
2016
Center for Advanced Research in Indian System of Medicine (CARISM), SASTRA University, Tanjavur, India: p.20.
11
Pharmacological evaluation of Standardized extract of Centella asciatica L. Urban leaves on Benign Prostatic Hyperplasia in male wistar rats [IND-19].
2015
48th Annual Conference of Indian Pharmacological Society, IPSCON2015, Saurashtra University, Rajkot, India, Indian Pharmacological Society,,47: p.S71.
12
Asiaticoside (INDCA) ameliorates cognitive impairment in chronic mild stress (CMS) model in wistar rats [NEU-27] [Best Poster award]
2015
48th Annual Conference of Indian Pharmacological Society, IPSCON2015, Saurashtra University, Rajkot, India, Indian Pharmacological Society,,47: p.S87.
13
Prenatal developmental toxicity study of furostanol glycoside based standardized extract from Trigonella foenum graecum in rats [IL42]
2015
Fifth Euro-India International Conference on Holistic Medicine (ICHM-2015) Kottayam, India, Institute for Holistic Medical Sciences (IHMS), Kottayam, Kerala, India.
14
Prenatal developmental toxicity study of procyanidine polyphenols from Cinnamomum zeylanicum (TAPP-CZ) in rats [Best Poster Award]
2015
Journal of Natural Product and Chemistry Research, HICC Hyderabad, India, OMICS international,3: p.6.
15
Prenatal Developmental Toxicity Study of Oligosaccharide Based Standardized Extract from Trigonella Foenum-Graecum in Rats [TOX-8]
2015
48th Annual Conference of Indian Pharmacological Society, IPSCON2015, Saurashtra University, Rajkot, India, Indian Pharmacological Society,,47: p.S146.
16
Preclinical toxicological evaluation of Trigonelline based standardized extract of Trigonella foenum-graecum L. seeds
2015
2nd International Conference on Biotechnology and Bioinformatics (ICBB-2015), Pune, India, International Center for Stem Cells, Cancer and Biotechnology (ICSCCB), Pune.
17
Preclinical toxicological evaluation of IDM01, a synergistic composition from Trigonella foenum-graecum L. seeds
2015
2nd International Congress of Society for Ethnopharmacology (SFEC - 2015) Nagpur, Society for Ethnopharmacology
18
Therapeutic potential of Synergistic composition from fenugreek seeds (Sugaheal?) against nonalcoholic steatohepatitis in C57BL/6 mice
2015
2nd International Congress of Society for Ethnopharmacology (SFEC - 2015) Nagpur, Society for Ethnopharmacology
19
Oligosaccharides based standardized fenugreek seed extract ameliorates nonalcoholic steatohepatitis in C57BL/6 mice (Best Poster Award)
2015
2nd International Conference on Biotechnology and Bioinformatics (ICBB-2015), Pune, India, International Center for Stem Cells, Cancer and Biotechnology (ICSCCB), Pune.
20
Evaluation of potential of standardized extract of Centella asiatica (L.) Urban leaves in epilepsy and associated post-ictal depression.
2015
2nd International Congress of Society for Ethnopharmacology (SFEC - 2015) Nagpur, Society for Ethnopharmacology
21
Inhibition of Hepatitis C Virus infection by IND02, a natural compound derived from Cinnamon [Best Poster Award]
2015
Single Theme Conference on HCV infection and disease and recent advances in liver diseases, New Delhi, India.
22
Efficacy of Oligosaccharides Based Standardized Fenugreek Seed Extract in Partial Sciatic Nerve Ligation Induced Peripheral Mononeuropathy in Rats [NEU-46]
2015
48th Annual Conference of Indian Pharmacological Society, IPSCON2015, Saurashtra University, Rajkot, India, Indian Pharmacological Society,,47: p.S92.
23
Mechanism based efficacy study of 4-Hydroxyisolucine from fenugreeks seeds on glucose and lipid metabolism in streptozotocin-induced diabetic rats [IL3}
2015
Fifth Euro-India International Conference on Holistic Medicine (ICHM-2015) Kottayam, India, Institute for Holistic Medical Sciences (IHMS), Kottayam, Kerala, India.
24
Efficacy of 4-Hydroxyisoleucine from Fenugreek seeds against central nervous system complications of Diabetes: In vivo and in vitro evidence
2015
First International Conference on Novel Frontiers in Pharmaceutical & Health Sciences (INNOPHARM1), Bhopal, Innovare Academic Sciences, India.
25
Synergistic composition of Fenugreek seed extract (Sugaheal?) ameliorates high-fat diet-induced insulin resistance in C57BL/6 mice via modulating the expression of leptin, Glut-2, Glut-4, IRS-2 and SREBP-1c
2015
2nd International Conference on Biotechnology and Bioinformatics (ICBB-2015), Pune, India, International Center for Stem Cells, Cancer and Biotechnology (ICSCCB), Pune.
26
Therapeutic efficacy of trigonelline-based standardized extract of fenugreek seeds on Levodopa induced dyskinesia in 6-OHDA lesioned rat model of Parkinson?s disease
2015
Journal of Natural Product and Chemistry Research, HICC Hyderabad, India, OMICS international,3: p.6.
27
Renoprotective effects of 4-hydroxyisoleucine from fenugreek seeds on diabetic nephropathy in rats: Role of mitochondrial antioxidant defense system [OP-54]
2015
International Symposium on New Perspectives in Modern Biotechnology (SAB-NPMB), The Accord Hotel, Puducherry (Pondicherry), India, Society of Applied Biotechnology.
28
Glycosides based standardized extract of fenugreek seeds ameliorates anti-glomerular basement membrane antibody-induced glomerulonephritis in rats
2015
2nd International Congress of Society for Ethnopharmacology (SFEC - 2015) Nagpur, Society for Ethnopharmacology
29
Preclinical toxicological evaluation of IDM01, a synergistic composition from Trigonella foenum-graecum L. seeds
2015
Nagpur Society for Ethnopharmacology:
30
Therapeutic potential of Synergistic composition from fenugreek seeds (Sugaheal®) against nonalcoholic steatohepatitis in C57BL/6 mice
2015
Nagpur Society for Ethnopharmacology:
31
Synergistic composition of Fenugreek seed extract (Sugaheal®) ameliorates high-fat diet-induced insulin resistance in C57BL/6 mice via modulating the expression of leptin, Glut-2, Glut-4, IRS-2 and SREBP-1c
2015
Pune, India International Center for Stem Cells, Cancer and Biotechnology (ICSCCB), Pune:
32
Therapeutic efficacy of trigonelline-based standardized extract of fenugreek seeds on Levodopa induced dyskinesia in 6-OHDA lesioned rat model of Parkinson’s disease
2015
HICC Hyderabad, India OMICS international, 3: p.6.
33
Mechanism based efficacy study of trigonelline based standardized fenugreek seed extract (IBHB) on levodopa induced dyskinesia in 6-hydroxydopamine lesioned rat model of Parkinson?s disease [P-81]
2014
2nd National Conference on ?Herbal and Synthetic Drug Studies (HSDS-2014), Azam Campus, Camp, Pune, Interdisciplinary Science and Technology research Academy (ISTRA), Azam Campus, Pune: p.65.
34
Androgenic and anabolic activity of glycoside based standardized fenugreek seeds extract on male Wistar rats
2014
APTICON2014- 19th Annual National Convention of Association of Pharmaceutical Teachers of India, Pune, India, Association of Pharmaceutical Teachers of India (APTI).
35
Mechanism based efficacy study of standardized extract of Centella asiatica (L.) Urban leaves on testosterone induced benign prostatic hyperplasia in male Wistar rats [PZM-2]
2014
47th Annual Conference of the Indian Pharmacological Society (IPSCON- 2014), Guwahati, India, Indian Pharmacological Society.
36
Preclinical toxicological evaluation of standardized extract of Centella asiatica (L.) Urban leaves [P-64]
2014
2nd National Conference on ?Herbal and Synthetic Drug Studies (HSDS-2014), Azam Campus, Camp, Pune, Interdisciplinary Science and Technology research Academy (ISTRA), Azam Campus, Pune: p.56.
37
Trigonelline [99%] - A promising antioxidant protecting against mitochondrial oxidative stress: an in vitro study [A-16]
2014
4th Annual Conference of the Society for Mitochondrial Research and Medicine, School of Life Sciences Manipal University, Manipal, India, Manipal University, Manipal, India: p.32.
38
Effects of Asiaticoside on 2,4,6-Trinitrobenzene Sulfonic Acid induced Experimental Colitis in Rats [GIT-4]
2014
47th Annual Conference of the Indian Pharmacological Society (IPSCON- 2014), Guwahati, India, Indian Pharmacological Society.
39
Renoprotective and anti-fibrotic efficacy of glycosides based standardized fenugreek seed extract (INDUS830) on unilateral ureteral obstruction induced renal interstitial fibrosis in mice
2014
2nd National Conference on ?Herbal and Synthetic Drug Studies (HSDS-2014), Azam Campus, Camp, Pune, Interdisciplinary Science and Technology research Academy (ISTRA), Azam Campus, Pune: p.42.
40
Mechanism based efficacy study of trigonelline based standardized fenugreek seed extract (IBHB) on levodopa induced dyskinesia in 6-hydroxydopamine lesioned rat model of Parkinson’s disease [P-81]
2014
Azam Campus, Camp, Pune Interdisciplinary Science and Technology research Academy (ISTRA), Azam Campus, Pune: p.65.
41
Effect of standardized extract of Centella asiatica (L.) Urban in experimental migraine and its possible mechanism of action [PZD-3]
2013
45th Annual Conference of Indian Pharmacological Society (IPSCON-2012) and International Conference on ?Navigating Pharmacology towards Safe and Effective Therapy?, Nagpur, Indian Pharmacological Society.
42
Evaluation of standardized extract of Centella asciatica leaves on suicidal behavior related traits in laboratory rats [PZD-3 received PC Dandiya Award]
2013
46th Annual Conference of Indian Pharmacological Society and International Conference on Translational Medicine, Bangalore, India, Indian Pharmacological Society.
43
Wound healing activity of type-A procyanidine polyphenols from cinnamon bark in amelioration of diabetes induced toxicity of foot ulcer in rats
2013
3rd Annual Conference of the Toxinological Society of India and 1st International Conference on ?Biology of Natural Toxins". BITS Pilani K K Birla Goa Campus, Goa, India, Toxinological Society of India.
44
Toxicological evaluations of the low molecular weight galactomannans from fenugreek seeds [OP-9]
2013
XXXIII Annual Conference of Society of Toxicology (STOX), Mathura, India.
45
Effect of Type-A procyanidine polyphenols from bark of Cinnamomum Zeylanicum on allergic rhinitis model in balb-c mice
2013
45th Annual Conference of Indian Pharmacological Society (IPSCON-2012) and International Conference on ?Navigating Pharmacology towards Safe and Effective Therapy?, Nagpur, Indian Pharmacological Society.
46
Pharmacokinetics study of asiaticoside after oral administration in rats (OR-14)
2013
National Conference on Advances in Bioanalytical Techniques (NCABT-2013) and Pharmaceutical Innovation for Domestic and Advanced Market: A Path Dependent Regulatory Approach (NCPIDAM-2013), Poona College of Pharmacy, Bharati Vidyapeeth Deemed University,
47
Toxicological evaluations of type-A procyanidine polyphenols from cinnamon bark [OP-10]
2013
XXXIII Annual Conference Of Society Of Toxicology (STOX), India For Synergy Of Toxicology Research In SAARC Countries Mathura, India.
48
Ameliorative effects of type-A procyanidine polyphenols from cinnamon bark in compound 48/80-induced systemic anaphylaxis and mast cell toxicity in-vivo and in-vitro.
2013
3rd Annual Conference of the Toxinological Society of India and 1st International Conference on ?Biology of Natural Toxins". BITS Pilani K K Birla Goa Campus, Goa, India, Toxinological Society of India.
49
Low molecular weight galactomannans from fenugreek seeds ameliorates high-fat diet-induced insulin resistance in C57BL/6 mice model via modulating the expression of Glut-2, Glut-4, IRS-2 and SREBP-1c [PZM-6]
2013
46th Annual Conference of Indian Pharmacological Society and International Conference on Translational Medicine, Bangalore, India, Indian Pharmacological Society.
50
Inhibition of Hepatitis C virus and HIV-1 by a cinnamon derived natural compound
2013
HepDART-2013, The Fairmont Orchid Hawaii, 1 North Kaniku Drive, Kohala Coast, The Big Island, Hawaii, USA
51
Inhibition of Hepatitis C virus infection by a natural compound derived from cinnamon
2013
International Symposium on Hepatitis C virus and Related Viruses (HCV-2013), Melbourne Convention and Exhibition Center, Melbourne, Australia.
52
A randomized placebo controlled study of standardized Cinnamon bark extract for prevention of breast cancer chemotherapy induced cachexia and alopecia
2013
45th Annual Conference of Indian Pharmacological Society (IPSCON-2012) and International Conference on ?Navigating Pharmacology towards Safe and Effective Therapy?, Nagpur, Indian Pharmacological Society.
53
Toxicological evaluation of flavonoid glycosides based standardized fenugreek seed extract [TOX/PP-15]
2013
46th Annual Conference of Indian Pharmacological Society and International Conference on Translational Medicine, Bangalore, India, Indian Pharmacological Society.
54
Ameliorative effect of low molecular weight galactomannans from fenugreek seeds in streptozotocin-induced diabetic neuropathy via modulation of electrophysiological, biochemical and behavioral markers
2013
Three day National Level seminar on recent advances in complementary and integrative medicines, Sinhagad Institute of Pharmaceutical Sciences, Lonavala, Sinhagad Institute of Pharmaceutical Sciences, Lonavala.
55
Anti-HIV and immune modulating activities of IND02
2012
AIDS Vaccine 2012, Boston Convention Center, Boston, USA.
56
Effects Of Fenugreek, Cinnamon, & Curcumin Supplementation On Post Workout Il6 And Cortisol Response
2010
Medicine & Science in Sports & Exercise,42: p.450.
57
Effects Of Fenugreek, Cinnamon, & Curcumin Supplementation On Post Workout Il6 And Cortisol Response: 1935
2010
Medicine & Science in Sports & Exercise,42: p.450.
58
Effects of TESTOSURGE supplementation on strength, body composition and hormonal profiles during an 8-week resistance training program
2009
Journal of the International Society of Sports Nutrition, New Orleans, LA, USA,6: p.P12.
59
Effects of Fenugreek, Cinnamon, & Curcumin on Post Workout Inflammatory Response
2009
International Journal of Exercise Science: Conference Proceedings,2: p.18.
60
Effects of BIOCREAT supplementation on strength and body composition during an 8-week resistance training program
2009
Journal of the International Society of Sports Nutrition,6: p.P11.
61
Fenugreek Extract Supplementation Has No Effect On The Hormonal Profile Of Resistance-trained Males: 2085
2009
Medicine & Science in Sports & Exercise,41: p.228.
62
Effects Of Fenugreek, Cinnamon, & Curcumin On Post Workout Inflammatory Response.: 2084
2009
Medicine & Science in Sports & Exercise,41: p.227.
63
Effects of Torabolic supplementation on strength and body composition during an 8-week resistance training program
2008
Journal of the International Society of Sports Nutrition,5: p.P11.
64
Study of galacetomennan on androgenic and anabolic activity in male rats
2007
IBRO sponsored International Structural Neuroscience Conference on Peptides, Nagpur.
65
Pharmacokinetic and pharmacodynamic study of trigonelline in normal and diabetic rats.
2007
IBRO sponsored International Structural Neuroscience Conference on Peptides, Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur.
66
IRA-01, an ayurvedic (Asian Indian) drug for rheumatoid arthritis (RA): evaluation for efficacy and safety, and a probable lipid modifying effect
2004
EULAR Annual European Congress of Rheumatology, Berlin, Germany, The European League Against Rheumatism (EULAR) p.Abstract no: FRI0088.
No results found